Litcius/Paper detail

Pre-T cell receptor self-MHC sampling restricts thymocyte dedifferentiation

Jonathan S. Duke‐Cohan, Aoi Akitsu, Robert J. Mallis, Cameron Messier, Patrick H. Lizotte, Jon C. Aster, Wonmuk Hwang, Matthew J. Lang, Ellis L. Reinherz

2022Nature23 citationsDOIOpen Access PDF

Topics & Concepts

ThymocyteBiologyCD8Double negativeMajor histocompatibility complexT cellCell biologyT-cell receptorImmunologyImmune systemCAR-T cell therapy researchT-cell and B-cell ImmunologyImmune Cell Function and Interaction