Real-Time In-Cell NMR Reveals the Intracellular Modulation of GTP-Bound Levels of RAS
Qingci Zhao, Ryu Fujimiya, S. Kubo, Christopher B. Marshall, Mitsuhiko Ikura, Ichio Shimada, N. Nishida
Abstract
of RAS are modulated by various intracellular factors.
Topics & Concepts
GTPaseGTP'IntracellularCytosolGuanosine diphosphateGuanosineGuanosine triphosphateCell biologySmall GTPaseMutantTriphosphataseGuanine nucleotide exchange factorSignal transductionCellBiochemistryChemistryBiologyEnzymeGeneIon channel regulation and functionErythrocyte Function and PathophysiologyProtein Kinase Regulation and GTPase Signaling