High social jetlag is correlated with nocturnal inhibition of melatonin production among night workers
R. P. O. Vieira, Patrícia Nehme, Elaine Cristina Marqueze, Fernanda Gaspar do Amaral, José Cipolla‐Neto, Cláudia Roberta de Castro Moreno
Abstract
) was used to assess chronotype. Urine was collected on workdays and days off to estimate the concentration of 6-sulfatoximelatonin (aMT6s), quantified by the ELISA method. We found SJL 13 times higher for night workers (10.6 h) than day workers (0.8 h). The excretion of aMT6s in night workers was statistically different on workdays as opposed to days off, with the lowest excretion on workdays, as expected. SJL was correlated with the aMT6s's delta between the night off and night on among night workers, indicating that the higher is the SJL, the lower is the melatonin production. As expected, social jetlag was higher among night workers, compared to day workers. Moreover, our findings showed that melatonin concentration is directly correlated with SJL.