Beneficial impact of cardiac heavy metal scavenger metallothionein in sepsis-provoked cardiac anomalies dependent upon regulation of endoplasmic reticulum stress and ferroptosis but not autophagy
Yuanzhuo Chen, Jian Zhao, Hua Ye, Asli F. Ceylan‐Isik, Bingfang Zhang, Qiong Liu, Yang Yang, Maolong Dong, Bijun Luo, Jun Ren
Topics & Concepts
AutophagyEndoplasmic reticulumUnfolded protein responseOxidative stressLipopolysaccharideInternal medicinep38 mitogen-activated protein kinasesGlutathioneEndocrinologyProinflammatory cytokineCell biologyChemistryMetallothioneinInflammationBiologyMedicineMAPK/ERK pathwayBiochemistrySignal transductionApoptosisGeneEnzymeFerroptosis and cancer prognosisTrace Elements in HealthClusterin in disease pathology