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Why the dual origins of high grade serous ovarian cancer matter

Emily K. Colvin, Viive M. Howell

2020Nature Communications17 citationsDOIOpen Access PDF

Abstract

Utilising identical genetic aberrations but targeting different cells, Zhang and colleagues seek to uncover how the cell of origin influences high-grade serous ovarian cancer biology, metastasis and response to treatment.

Topics & Concepts

Serous ovarian cancerOvarian cancerSerous fluidZhàngClear cellBiologyCancer researchMetastasisMedicineBioinformaticsCancerGeneticsPathologyCarcinomaLawPolitical scienceChinaOvarian cancer diagnosis and treatmentCancer-related molecular mechanisms researchRNA modifications and cancer
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