WNT16 is upregulated early in mouse TMJ osteoarthritis and protects fibrochondrocytes against IL-1β induced inflammatory response by regulation of RUNX2/MMP13 cascade
Xianwen Liu, Xinping Li, Bingqiang Hua, Xiaoqin Yang, Junfa Zheng, Shuguang Liu
Topics & Concepts
Wnt signaling pathwayOsteoarthritisDownregulation and upregulationRUNX2CartilageHomeostasisMedicineInternal medicineEndocrinologyChemistryCell biologySignal transductionAnatomyPathologyGene expressionBiologyGeneAlternative medicineBiochemistryOsteoarthritis Treatment and MechanismsProteoglycans and glycosaminoglycans researchCell Adhesion Molecules Research