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Synthesis of hyaluronic acid hydrogels by crosslinking the mixture of high-molecular-weight hyaluronic acid and low-molecular-weight hyaluronic acid with 1,4-butanediol diglycidyl ether

Yu Xue, Hongyue Chen, Chao Xu, Dinghua Yu, Hua‐Jin Xu, Yi Hu

2020RSC Advances101 citationsDOIOpen Access PDF

Abstract

anti-degradation ability, better mechanical properties and lower cytotoxicity than those prepared by mixing in different proportions. Hydrogel B has potential applications in regenerative medicine and tissue engineering.

Topics & Concepts

Hyaluronic acidDiglycidyl etherSelf-healing hydrogelsChemistrySwellingCytotoxicityPolymer chemistryMolecular massNuclear chemistryBiochemistryChemical engineeringIn vitroOrganic chemistryEnzymeBiologyEngineeringBisphenol AEpoxyGeneticsProteoglycans and glycosaminoglycans researchHydrogels: synthesis, properties, applicationsPolysaccharides Composition and Applications
Synthesis of hyaluronic acid hydrogels by crosslinking the mixture of high-molecular-weight hyaluronic acid and low-molecular-weight hyaluronic acid with 1,4-butanediol diglycidyl ether | Litcius