Green-light-responsive metal–organic frameworks for colorectal cancer treatment
Hannah D. Cornell, Yumeng Zhu, Stefan Ilić, Naomei E. Lidman, Xiaozhou Yang, John B. Matson, Amanda J. Morris
Abstract
Herein, the synthetic methods for preparation of a novel light-responsive metal-organic framework (MOF) UiO-AZB-F are outlined. Upon irradiation with green light, the framework demonstrates controlled release of chemotherapeutic drug cargo with simultaneous breakdown into low toxicity small molecule components.
Topics & Concepts
Metal-organic frameworkOrganic moleculesMaterials scienceNanotechnologyMetalColorectal cancerMoleculeCombinatorial chemistryCancerChemistryOrganic chemistryMedicineAdsorptionMetallurgyInternal medicineNanoplatforms for cancer theranosticsMetal-Organic Frameworks: Synthesis and ApplicationsAdvanced Nanomaterials in Catalysis