The RTS,S malaria vaccine: Current impact and foundation for the future
James G. Beeson, Liriye Kurtovic, Clarissa Valim, Kwaku Poku Asante, Michelle J. Boyle, Don P. Mathanga, Carlota Dobaño, Gemma Moncunill
Abstract
The RTS,S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria transmission. We discuss mechanisms of vaccine protection and longevity, implementation considerations, and future research needed to increase the vaccine's health impact, including vaccine modifications for higher efficacy and longevity of protection.
Topics & Concepts
Malaria vaccineLongevityMalariaMedicineVirologyTransmission (telecommunications)ImmunologyEnvironmental healthGerontologyPlasmodium falciparumComputer scienceTelecommunicationsMalaria Research and ControlMosquito-borne diseases and controlParasites and Host Interactions