A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells
Bagineni Prasad, Mara Doimo, Måns Andréasson, Valentin L’Hôte, Erik Chorell, Sjoerd Wanrooij
Abstract
as delivery vehicles. The applied approach to generate multiple tailored biochemical tools based on the same core structure can thus be used to advance the studies of G4 biology to uncover molecular details and therapeutic approaches.
Topics & Concepts
FluorophoreChemistryConjugatePeptideCombinatorial chemistryDNAConjugated systemChemical biologyBiophysicsAmine gas treatingSelectivityFluorescenceDerivative (finance)BODIPYComputational biologyBiochemistryBiologyPhysicsMathematicsFinancial economicsOrganic chemistryMathematical analysisEconomicsQuantum mechanicsCatalysisPolymerDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery