Synthesis and clinical application of small-molecule inhibitors of Janus kinase
Jingyi Zhang, Jinfeng Sun, Peng Nie, Piet Herdewijn, Yatao Wang
Topics & Concepts
Janus kinaseSmall moleculeClinical trialDrug developmentDrug discoveryChemistrySignal transductionDrugKinasePharmacologyComputational biologyCancer researchMedicineBioinformaticsBiologyBiochemistryCytokine Signaling Pathways and InteractionsMyeloproliferative Neoplasms: Diagnosis and TreatmentPharmacological Effects of Natural Compounds