Anti–CD19 CAR T Cells in Refractory Immune Thrombocytopenia of SLE
Mengtao Li, Yan Zhang, Nan Jiang, Chun Ning, Qian Wang, Dong Xu, Ziqian Wang, Lulu Lv, Daobin Zhou, Xiaofeng Zeng
Abstract
A woman with refractory thrombocytopenia complicating systemic lupus erythematosus had a response to CD19 CAR T cells with an increase in platelet counts and minimal symptoms of cytokine release syndrome.
Topics & Concepts
CD19Immune thrombocytopeniaRefractory (planetary science)Immune systemImmunologyMedicineAntibodyBiologyAstrobiologyCAR-T cell therapy researchPlatelet Disorders and TreatmentsChronic Lymphocytic Leukemia Research