Omega-3 Polyunsaturated Fatty Acids Protect Neurological Function After Traumatic Brain Injury by Suppressing Microglial Transformation to the Proinflammatory Phenotype and Activating Exosomal NGF/TrkA Signaling
Long Lin, Shaorui Zheng, Jinqing Lai, Dan Ye, Qiaomei Huang, Zhe Wu, Xiangrong Chen, Shousen Wang
Topics & Concepts
NeuroprotectionNeuroinflammationTraumatic brain injuryProinflammatory cytokineNeurodegenerationPolyunsaturated fatty acidMicrogliaNerve growth factorTumor necrosis factor alphaPharmacologyTropomyosin receptor kinase AMedicineImmunologyInflammationCancer researchBiologyInternal medicineReceptorBiochemistryDiseaseFatty acidPsychiatryNeuroinflammation and Neurodegeneration MechanismsExtracellular vesicles in diseaseImmune Response and Inflammation