Water-soluble bright NIR AIEgens with hybrid ROS for wash-free mitochondrial “off–on” imaging and photodynamic therapy
Fangzhou Xu, Chengyun Wang, Qi Wang, Jian‐Wei Zou, Yi-Jie Qiao, Zhiqian Guo, Weijun Zhao, Weihong Zhu
Abstract
The AIEgen TEPP exhibits both bright near-infrared emission ( φ F = 17.8%) and high hybrid ROS productivity (including OH˙ and 1 O 2 ).
Topics & Concepts
Photodynamic therapyAggregation-induced emissionHeLaChemistryNear-infrared spectroscopyPhotochemistryFluorescenceIn vitroBiochemistryOpticsOrganic chemistryPhysicsLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranosticsMolecular Sensors and Ion Detection