Melatonin reduces neuropathic pain behavior and glial activation through MT2 melatonin receptor modulation in a rat model of lysophosphatidylcholine-induced demyelination neuropathy
Chun‐Ta Huang, Seu‐Hwa Chen, Chi-Fen Chang, Shih‐Chang Lin, June‐Horng Lue, Yi‐Ju Tsai
Topics & Concepts
Glial fibrillary acidic proteinEndocrinologyInternal medicineMelatoninAstrocyteMelatonin receptorNeuropathic painMicrogliaReceptor antagonistMAPK/ERK pathwayMedicineAntagonistReceptorBiologyPharmacologySignal transductionInflammationCentral nervous systemImmunohistochemistryCell biologyPain Mechanisms and TreatmentsPharmacological Effects of Natural CompoundsDermatology and Skin Diseases