Apigenin by targeting hnRNPA2 sensitizes triple-negative breast cancer spheroids to doxorubicin-induced apoptosis and regulates expression of ABCC4 and ABCG2 drug efflux transporters
Meenakshi Sudhakaran, Michael Ramirez Parra, Hayden Stoub, Kathleen A. Gallo, Andrea I. Doseff
Topics & Concepts
ApigeninTriple-negative breast cancerCancer researchApoptosisGene silencingDoxorubicinChemistryEffluxPharmacologyBiologyCell biologyBiochemistryBreast cancerCancerChemotherapyGeneticsAntioxidantFlavonoidGeneDrug Transport and Resistance MechanismsDNA Repair MechanismsRNA and protein synthesis mechanisms