Insights into the inhibitory mechanism of purpurogallin on xanthine oxidase by multiple spectroscopic techniques and molecular docking
Jin Wang, Shiwei Sun, Ke Zhao, Hai-Lin Shi, Jiahe Fan, Hui Wang, Yang Liu, Xiaohong Liu, Wei Wang
Topics & Concepts
ChemistryCircular dichroismXanthine oxidaseHydrogen bondRandom coilvan der Waals forceQuenching (fluorescence)StereochemistryTryptophanFluorescenceBiochemistryEnzymeOrganic chemistryAmino acidMoleculePhysicsQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisGout, Hyperuricemia, Uric AcidDrug Transport and Resistance Mechanisms