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Hypoparathyroidism: An Uncommon Complication Associated With Immune Checkpoint Inhibitor Therapy

Omar El Kawkgi, Dingfeng Li, Anupam Kotwal, Robert A. Wermers

2020Mayo Clinic Proceedings Innovations Quality & Outcomes33 citationsDOIOpen Access PDF

Abstract

As immune checkpoint inhibitor drugs are being used in the treatment of some cancers, unusual adverse events are being reported, labeled as immune-related adverse events. Various endocrinopathies related to immune-related adverse events have been described, among which hypoparathyroidism is exceedingly rare. We report a case of hypoparathyroidism induced by immune checkpoint drugs, highlighting the need for awareness of this emerging complication.

Topics & Concepts

HypoparathyroidismAdverse effectComplicationMedicineImmune systemImmune checkpointImmunologyInternal medicineImmunotherapyCancer Immunotherapy and BiomarkersNeuroendocrine Tumor Research AdvancesCancer Diagnosis and Treatment
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