Litcius/Paper detail

Active-site cysteine 215 sulfonation targets protein tyrosine phosphatase PTP1B for Cullin1 E3 ligase-mediated degradation

Chunyi Yang, Chiu-Fen Yang, Xiaofang Tang, Luciana E. S. F. Machado, Jai Prakash Singh, Wolfgang Peti, Chien‐Sheng Chen, Tzu‐Ching Meng

2022Free Radical Biology and Medicine12 citationsDOI

Topics & Concepts

Ubiquitin ligaseUbiquitinChemistryProteasomeProtein tyrosine phosphataseBiochemistryPhosphataseCell biologyProtein degradationCysteineReactive oxygen speciesTyrosineEnzymeBiologyGeneProtein Tyrosine PhosphatasesRNA modifications and cancerUbiquitin and proteasome pathways