TGF-β1-modified MSC-derived exosomal miR-135b attenuates cartilage injury via promoting M2 synovial macrophage polarization by targeting MAPK6
Rui Wang, Bin Xu
Topics & Concepts
CartilageMesenchymal stem cellOsteoarthritisExosomeChemistryBone marrowInflammationDownregulation and upregulationMacrophage polarizationCell biologyMicrovesiclesCancer researchMacrophageMedicinePathologyImmunologymicroRNABiologyAnatomyIn vitroBiochemistryAlternative medicineGeneExtracellular vesicles in diseaseBone and Joint DiseasesOsteoarthritis Treatment and Mechanisms