An HDAC6 inhibitor reverses chemotherapy-induced mechanical hypersensitivity via an IL-10 and macrophage dependent pathway
Jixiang Zhang, Jiacheng Ma, Ronnie The Phong Trinh, Cobi J. Heijnen, Annemieke Kavelaars
Topics & Concepts
HDAC6MicrogliaPharmacologyCisplatinMedicineChemotherapy-induced peripheral neuropathyImmunologyChemotherapyCancer researchChemistryPeripheral neuropathyEndocrinologyInternal medicineInflammationHistone deacetylaseBiochemistryGeneDiabetes mellitusHistoneHistone Deacetylase Inhibitors ResearchCancer Treatment and PharmacologyPain Mechanisms and Treatments