Identification of embryonic RNA granules that act as sites of mRNA translation after changing their physical properties
Keisuke Sato, Moeko Sakai, Anna Ishii, Kaori Maehata, Yuki Takada, Kyota Yasuda, Tomoya Kotani
Abstract
mRNA in mouse assembled into granules. Our results reveal that subcellular compartments, termed embryonic RNA granules, function as activation sites of translation after changing physical properties for directing vertebrate development.
Topics & Concepts
ZebrafishMessenger RNAP-bodiesProtein biosynthesisCell biologyTranslation (biology)RNABiologyRibosomal RNAChemistryMolecular biologyBiochemistryGeneRNA Research and SplicingRNA modifications and cancerMicroRNA in disease regulation