miRNA-29a reverses P-glycoprotein-mediated drug resistance and inhibits proliferation via up-regulation of PTEN in colon cancer cells
Xiaoxin Shi, Amir Valizadeh, Seyed Mostafa Mir, Zatollah Asemi, Ansar Karimian, Maryam Majidina, Amin Safa, Bahman Yosefi
Topics & Concepts
PTENmicroRNACancer researchPI3K/AKT/mTOR pathwayTransfectionCell growthBiologyViability assayCancer cellFlow cytometryApoptosisCancerPharmacologyMolecular biologyCell cultureBiochemistryGeneGeneticsMicroRNA in disease regulationCancer-related molecular mechanisms researchRNA modifications and cancer