Hyperoside attenuates pyrrolizidine alkaloids-induced liver injury by ameliorating TFEB-mediated mitochondrial dysfunction
Jie Xu, Aizhen Xiong, Xunjiang Wang, Xing Yan, Yilin Chen, Xuanling Ye, Zhengtao Wang, Lili Ding, Li Yang
Topics & Concepts
TFEBAutophagyPharmacologyLiver injuryMitochondrial biogenesisChemistrymTORC1HepatoprotectionMechanistic target of rapamycinBiochemistryMitochondrionBiologyPI3K/AKT/mTOR pathwaySignal transductionGlutathioneApoptosisEnzymeDrug-Induced Hepatotoxicity and ProtectionPlant Toxicity and Pharmacological PropertiesAldose Reductase and Taurine