Empagliflozin alleviates endoplasmic reticulum stress and augments autophagy in rotenone-induced Parkinson's disease in rats: Targeting the GRP78/PERK/eIF2α/CHOP pathway and miR-211-5p
Tarek K. Motawi, Rawan H. Al-Kady, Sahar M. Abdelraouf, Mahmoud A. Senousy
Topics & Concepts
Unfolded protein responseNeuroprotectionEndoplasmic reticulumRotenoneAutophagyPharmacologyCHOPNeurodegenerationOxidative stressEndocrinologyMedicineInternal medicineChemistryBiologyCell biologyApoptosisMitochondrionBiochemistryDiseaseEndoplasmic Reticulum Stress and DiseaseParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy