Single-nucleus RNA sequencing identifies cell-type–specific effects of sodium-glucose co-transporter 2 inhibitors in human myocardial slices
Kevin Schmidt, Maximilian Fuchs, Natalie Weber, Christopher Werlein, Jan D. Schmitto, F. Ius, Arjang Ruhparwar, Christian Bär, Jan Fiedler, Thomas Thum
Abstract
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Topics & Concepts
MedicineTransporterRNAGlucose transporterCellPharmacologyRNA-SeqSodiumCell typeInternal medicineGene expressionBiochemistryGeneTranscriptomeInsulinOrganic chemistryChemistryDiabetes Treatment and ManagementPancreatic function and diabetesMetabolism, Diabetes, and Cancer