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IGF2BP1 overexpression stabilizes PEG10 mRNA in an m6A-dependent manner and promotes endometrial cancer progression

Lin Zhang, Yicong Wan, Zihan Zhang, Yi Jiang, Zhiyue Gu, Xiaoling Ma, Sipei Nie, Jing Yang, Jinghe Lang, Wenjun Cheng, Lan Zhu

2020Theranostics280 citationsDOIOpen Access PDF

Abstract

A-dependent regulatory mechanism for endometrial cancer. This study provides new insights into our understanding of disease progression and provides another potential route for understanding biological functions.

Topics & Concepts

Messenger RNAEndometrial cancerCancer researchCancerChemistryBiologyCell biologyMedicineInternal medicineGeneGeneticsRNA modifications and cancerCancer-related gene regulationRNA Research and Splicing
IGF2BP1 overexpression stabilizes PEG10 mRNA in an m6A-dependent manner and promotes endometrial cancer progression | Litcius