Boosting Natural Killer Cell-Based Cancer Immunotherapy with Selenocystine/Transforming Growth Factor-Beta Inhibitor-Encapsulated Nanoemulsion
Chang Liu, Haoqiang Lai, Tianfeng Chen
Abstract
. Together, this study not only demonstrates a simple strategy for the design of a nanoemulsion to co-deliver synergistic drugs but also sheds light on the application and action mechanisms in NK cell adaptive therapy against breast cancer, especially TNBCs.
Topics & Concepts
NKG2DCancer researchImmunotherapyCancer immunotherapyImmune systemNatural killer cellCancer cellTumor microenvironmentTransforming growth factor betaCytotoxicityImmunologyChemistryTransforming growth factorCancerBiologyCell biologyIn vitroBiochemistryGeneticsImmune Cell Function and InteractionImmune cells in cancerImmunotherapy and Immune Responses