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Metal‐Free SF<sub>6</sub>Activation: A New SF<sub>5</sub>‐Based Reagent Enables Deoxyfluorination and Pentafluorosulfanylation Reactions

Alexis Taponard, Tristan Jarrosson, Lhoussain Khrouz, Maurice Médebielle, Julie Broggi, Anis Tlili

2022Angewandte Chemie International Edition92 citationsDOIOpen Access PDF

Abstract

Abstract The activation of SF 6 , a potent greenhouse gas, under metal‐free and visible light conditions is reported. Herein, mechanistic investigations including EPR spectroscopy, NMR studies and cyclic voltammetry allowed the rational design of a new fluorinating reagent which was synthesized from the 2‐electron activation of SF 6 with commercially available TDAE. This new SF 5 ‐based reagent was efficiently employed for the deoxyfluorination of CO 2 and the fluorinative desulfurization of CS 2 allowing the formation of useful fluorinated amines. Moreover, for the first time we demonstrated that our SF 5 ‐based reagent could afford the mild generation of Cl‐SF 5 gas. This finding was exploited for the chloro‐pentafluorosulfanylation of alkynes and alkenes.

Topics & Concepts

ReagentChemistryElectron paramagnetic resonanceFlue-gas desulfurizationCyclic voltammetryMetalCombinatorial chemistryPhotochemistryOrganic chemistryElectrochemistryElectrodePhysical chemistryNuclear magnetic resonancePhysicsFluorine in Organic ChemistryCarbon dioxide utilization in catalysisInorganic Fluorides and Related Compounds
Metal‐Free SF<sub>6</sub>Activation: A New SF<sub>5</sub>‐Based Reagent Enables Deoxyfluorination and Pentafluorosulfanylation Reactions | Litcius