Modelling studies reveal the importance of the C-terminal inter motif loop of NSP1 as a promising target site for drug discovery and screening of potential phytochemicals to combat SARS-CoV-2
Dhamodharan Prabhu, Sundaraj Rajamanikandan, Muthusamy Sureshan, Jeyaraman Jeyakanthan, K. Saraboji
Topics & Concepts
Drug discoveryComputational biologyBiologyViral replicationDocking (animal)Binding siteRibosomal binding siteRibosome profilingRibosomeCoronavirusStructural motifCell biologyRNAGeneGeneticsBioinformaticsVirusBiochemistryCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)NursingPathologyMedicineDiseaseComputational Drug Discovery MethodsBiochemical and Structural CharacterizationPlant-based Medicinal Research