Synthesis and evaluation of sulfonyl piperazine LpxH inhibitors
Seung‐Hwa Kwak, C. Skyler Cochrane, Amanda F. Ennis, Won Young Lim, Caroline G. Webster, Jae Cho, Benjamin Fenton, Pei Zhou, Jiyong Hong
Topics & Concepts
PiperazineSulfonylChemistryLigand (biochemistry)StereochemistryHydrolaseActive siteCombinatorial chemistryEnzymeBiochemistryReceptorOrganic chemistryAlkylRNA and protein synthesis mechanismsAntibiotic Resistance in BacteriaEnzyme Structure and Function