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Fermented noni (<i>Morinda citrifolia</i> L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells

Xuguang Zhang, Bin Zhang, Li Li, Xiaobao Li, Junqing Zhang, Guang‐Ying Chen

2022Food & Function28 citationsDOI

Abstract

. These results confirmed that FNJ had a protective effect on oxidative stress and IR by activating Nrf2/ARE signaling pathway and regulating gut flora in db/db mice and IR-HepG2 cells.

Topics & Concepts

MorindaOxidative stressFood scienceInsulin resistanceFermentationFlora (microbiology)ChemistryTraditional medicineBiologyInsulinMedicineBiotechnologyBiochemistryBacteriaGeneticsMorinda citrifolia extract usesPharmacological Effects of Natural CompoundsVitamin C and Antioxidants Research
Fermented noni (<i>Morinda citrifolia</i> L.) fruit juice improved oxidative stress and insulin resistance under the synergistic effect of Nrf2/ARE pathway and gut flora in db/db mice and HepG2 cells | Litcius