First Detection of Monkeypox Virus Genome in Sewersheds in France: The Potential of Wastewater-Based Epidemiology for Monitoring Emerging Disease
Sébastien Wurtzer, Morgane Levert, Eloïse Dhenain, Mickaël Boni, Jean‐Nicolas Tournier, Nicolas Londinsky, Agnès Lefranc, OBEPINE SIG, Olivier Ferraris, Laurent Moulin
Abstract
A monkeypox virus outbreak has been spreading in multiple nonendemic countries since May 2022. The atypical clinical profile of patients has led to a very likely underestimation of the number of cases at the beginning of the epidemic. The detection and quantification of the Monkeypox virus genome in sewersheds in Paris (France) correlated temporally with the identification of the first case of infection and the spread of the disease within the population connected to the sewage system.
Topics & Concepts
MonkeypoxOutbreakVirologyEpidemiologyVirusDiseasePopulationBiologyNovel virusGenomeMedicineEnvironmental healthVacciniaGeneticsGenePathologyRecombinant DNAPoxvirus research and outbreaksBacillus and Francisella bacterial researchBacteriophages and microbial interactions