Design, synthesis and in-vitro evaluation of fluorinated triazoles as multi-target directed ligands for Alzheimer disease
Tanay Dalvi, Bhaskar Dewangan, Gopal Agarwal, Dattatray Shinde Suchita, Alok Jain, Akshay Srivastava, Bichismita Sahu
Topics & Concepts
ChemistryReactive oxygen speciesDrug discoveryPharmacologyMoietyIn vitroDocking (animal)Alzheimer's diseaseBlood–brain barrierIC50BiochemistryStereochemistryBiophysicsDiseaseNeuroscienceBiologyNursingPathologyCentral nervous systemMedicineAlzheimer's disease research and treatmentsTryptophan and brain disordersCholinesterase and Neurodegenerative Diseases