Custom CRISPR–Cas9 PAM variants via scalable engineering and machine learning

Rachel A. Silverstein, Nahye Kim, Ann-Sophie Kroell, Russell T. Walton, Justin Delano, Rossano Butcher, Martin Pačesa, Baz Smith, Kathleen A. Christie, Leillani L. Ha, Ronald J. Meis, Aaron B. Clark, Aviv D. Spinner, Cícera R. Lazzarotto, Yichao Li, Azusa Matsubara, Elizabeth Urbina-Sánchez, Gary A. Dahl, Bruno E. Correia, Debora S. Marks, Shengdar Q. Tsai, Luca Pinello, Suk See De Ravin, Qin Liu, Benjamin P. Kleinstiver