OvoA<sub>Mtht</sub>from<i>Methyloversatilis thermotolerans</i>ovothiol biosynthesis is a bifunction enzyme: thiol oxygenase and sulfoxide synthase activities
Ronghai Cheng, Andrew C. Weitz, Jared C. Paris, Yijie Tang, Jingyu Zhang, Heng Song, Nathchar Naowarojna, Kelin Li, Lu Qiao, Juan Lopez, Mark W. Grinstaff, Lixin Zhang, Yisong Guo, Sean J. Elliott, Pinghua Liu
Abstract
is an excellent system for future detailed mechanistic investigation on how metal ligands and secondary coordination shell residues fine-tune the iron-center electronic properties to achieve different reactivities.
Topics & Concepts
ATP synthaseChemistryEnzymeThiolHemeSulfoxideCysteineBiochemistryHeme oxygenaseHistidineOxygenaseStereochemistryOrganic chemistryMetal-Catalyzed Oxygenation MechanismsMetalloenzymes and iron-sulfur proteinsCassava research and cyanide