Jieduquyuziyin prescription enhances CD11a and CD70 DNA methylation of CD4+ T cells via miR-29b-sp1/DNMT1 pathway in MRL/lpr mice
Shuo Huang, Jiaqi Peng, Yihong Gan, Leiming Chen, Zhengyang Zhu, Fengyuan Tian, Lina Ji, Yongsheng Fan, Chuanlong Zhou, Jie Bao
Topics & Concepts
DNA methylationMethylationTraditional Chinese medicineDemethylating agentMolecular biologyDNMT1Western blotJurkat cellsImmunologyPharmacologyMedicineBiologyCancer researchMethyltransferaseImmune systemT cellDNAGene expressionPathologyGeneBiochemistryAlternative medicineSystemic Lupus Erythematosus ResearchT-cell and B-cell ImmunologySingle-cell and spatial transcriptomics