Litcius/Paper detail

Discovery of anti-inflammatory agents from 3, 4-dihydronaphthalene-1(2H)-one derivatives by inhibiting NLRP3 inflammasome activation

Wen-Xuan Li, Lu Yu, Jiang-Bo Chi, Jipeng Wang, Yongjun Liu, Chunhua Wang, Meng Zhang, Gui‐Ge Hou

2024European Journal of Medicinal Chemistry16 citationsDOI

Topics & Concepts

ChemistryInflammasomePyrin domainDocking (animal)Reactive oxygen speciesSignal transductionReceptorBiochemistryNursingMedicineInflammasome and immune disordersSphingolipid Metabolism and Signalinginterferon and immune responses