Hyperactivity of Purkinje cell and motor deficits in C9orf72 knockout mice
Yuning Liu, Hong Xing, Alexis T. Ernst, Canna Liu, Christian Maugee, Fumiaki Yokoi, Madepalli K. Lakshmana, Yuqing Li
Topics & Concepts
C9orf72CerebellumPurkinje cellBiologyNeuroscienceKnockout mouseAmyotrophic lateral sclerosisFrontotemporal dementiaTrinucleotide repeat expansionGeneticsInternal medicineMedicineGeneDementiaDiseaseAlleleAmyotrophic Lateral Sclerosis ResearchParkinson's Disease Mechanisms and TreatmentsCholinesterase and Neurodegenerative Diseases