ITLN1 inhibits tumor neovascularization and myeloid derived suppressor cells accumulation in colorectal carcinoma
Li Chen, Xiaohan Jin, Jie Luo, Jin‐Ling Duan, Muyan Cai, Jiewei Chen, Zihao Feng, Austin M. Guo, Feng‐Wei Wang, Dan Xie
Topics & Concepts
Cancer researchBiologyBone marrowMyeloid-derived Suppressor CellTumor microenvironmentColorectal cancerPI3K/AKT/mTOR pathwayCXCL2AngiogenesisCXCL1Progenitor cellHaematopoiesisImmunologyStem cellCancerChemokineSuppressorImmune systemSignal transductionChemokine receptorCell biologyTumor cellsGeneticsImmune cells in cancerImmune Cell Function and InteractionCancer Immunotherapy and Biomarkers