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Low‐Cost Transition Metal‐Catalyzed Heck‐Type Reactions: An Overview

Mathews Alisha, Rose Mary Philip, Gopinathan Anilkumar

2022European Journal of Organic Chemistry28 citationsDOI

Abstract

Abstract Heck coupling has emerged as an effective and powerful tool for C−C bond formations, with applications in academic and industrial grounds. The conventional Mizoroki‐Heck reaction employed expensive Pd based catalysts, however, developments to meet low‐cost replacements to Pd is relevant from a sustainable point of view. Heck‐type couplings involving cost‐effective transition metals such as Fe, Co, Ni, and Cu have been established in the recent decades. Herein, we have comprehended the developments in low‐cost transition metal‐catalyzed Heck couplings covering the literature from 2016.

Topics & Concepts

Heck reactionChemistryTransition metalCatalysisPalladiumCombinatorial chemistryOrganic chemistryNanotechnologyMaterials scienceCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and Catalysis