General Mechanochemical Synthetic Protocol to Late Transition Metal–NHC (<i>N</i>-Heterocyclic Carbene) Complexes
Gianmarco Pisanò, Catherine S. J. Cazin
Abstract
A user-friendly and highly efficient mechanochemical strategy for the synthesis of a number of well-defined, catalytically relevant N-heterocyclic carbene–metal complexes under aerobic conditions is reported. This protocol proceeds in good to excellent yields and limits solvent usage to the purification step, which can be carried out, after judicious selection, using minimal amounts of environmentally benign solvents.
Topics & Concepts
CarbeneTransition metalChemistryCombinatorial chemistrySolventEnvironmentally friendlyMetalCatalysisOrganic chemistryBiologyEcologyN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCarbon dioxide utilization in catalysis