Litcius/Paper detail

Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging

Zer Vue, Kit Neikirk, Larry Vang, Edgar Garza-López, Trace Christensen, Jianqiang Shao, Jacob Lam, Heather K. Beasley, Andrea G. Marshall, Amber Crabtree, Josephs Anudokem, Blanca Rodríguez, Benjamin Kirk, Serif Bacevac, Taylor Barongan, Bryanna Shao, Dominique C. Stephens, Kinuthia Kabugi, Ho‐Jin Koh, Alice Koh, Chantell S. Evans, Brittany Taylor, Anilkumar K. Reddy, Tyne W. Miller‐Fleming, Ky’Era V. Actkins, Elma Zaganjor, Nastaran Daneshgar, Sandra Murray, Bret C. Mobley, Steven M. Damo, Jennifer A. Gaddy, Blake Riggs, Celestine N. Wanjalla, Annet Kirabo, Melanie R. McReynolds, José A. Gómez, Mark Phillips, Vernat Exil, Dao‐Fu Dai, Antentor Hinton

2023American Journal of Physiology-Heart and Circulatory Physiology57 citationsDOIOpen Access PDF

Abstract

This article shows how mitochondria in murine cardiac changes, importantly elucidating age-related changes. It also is the first to show that the MICOS complex may play a role in outer membrane mitochondrial structure.

Topics & Concepts

MitochondrionCardiac muscleCell biologyBiologyChemistryAnatomyMitochondrial Function and PathologyATP Synthase and ATPases ResearchMetabolism and Genetic Disorders