ALS/FTLD-Linked Mutations in FUS Glycine Residues Cause Accelerated Gelation and Reduced Interactions with Wild-Type FUS
Kevin Rhine, Monika A. Makurath, James Liu, Sophie Skanchy, Christian Lopez, Kevin F. Catalan, Ye Ma, Charlotte M. Fare, James Shorter, Taekjip Ha, Yann R. Chemla, Sua Myong
Topics & Concepts
BiologyMutantFrontotemporal lobar degenerationWild typeAmyotrophic lateral sclerosisMutationRNAPathogenesisMolecular biologyGeneticsCell biologyFrontotemporal dementiaGeneDementiaDiseasePathologyImmunologyMedicineRNA Research and SplicingAmyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research