DTX2 attenuates Lenvatinib-induced ferroptosis by suppressing docosahexaenoic acid biosynthesis through HSD17B4-dependent peroxisomal β-oxidation in hepatocellular carcinoma
Zhongyan Zhang, Qi Zhou, Zhenchong Li, Fuxin Huang, Ke Mo, Cheng Shen, Xing Niu, Baohua Hou, Chuanzhao Zhang, Shanzhou� Huang, Chuanzhao Zhang, Shanzhou� Huang
Topics & Concepts
Docosahexaenoic acidHepatocellular carcinomaLenvatinibPeroxisomeChemistryCancer researchDownregulation and upregulationCell biologyBiochemistryInternal medicineBiologyReceptorMedicinePolyunsaturated fatty acidFatty acidGeneSorafenibFerroptosis and cancer prognosisImmune cells in cancerCancer, Lipids, and Metabolism