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Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway

Shahad W. Kattan, Mohamed S. Nafie, Gamal A. Elmgeed, Walla Alelwani, Muhammad Badar, Mohamed A. Tantawy

2020The Journal of Steroid Biochemistry and Molecular Biology73 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayProtein kinase BMTT assayApoptosisDNA fragmentationCell cycleChemistryCell growthCancer researchBiologyPharmacologyBiochemistryProgrammed cell deathHormonal Regulation and HypertensionFree Radicals and AntioxidantsComputational Drug Discovery Methods
Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway | Litcius