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Return on investment of rapid ICU workforce upskilling: an economic and cost-effectiveness analysis

Claudia Ebm, Melania Istrate, F Van Gelder, Gergő József Szöllösi, Joel Alexandre, Élie Azoulay, Jozef Kesecioğlu, Maurizio Cecconi

2025Intensive Care Medicine7 citationsDOIOpen Access PDF

Abstract

PURPOSE: Although healthcare crises are infrequent, they may place extraordinary stress on Intensive Care Units (ICUs), often exposing critical weaknesses in workforce planning and resulting in acute staffing shortages. This study presents a comprehensive economic evaluation of large-scale, rapid ICU workforce upskilling as a strategic response to such pressures. Specifically, we assess the cost-effectiveness, economic sustainability, and resilience-building potential of these interventions during crisis conditions. METHODS: C19_SPACE, a Europe-wide upskilling initiative led by the European Society of Intensive Care Medicine (ESICM), was implemented across 24 countries between 2020 and 2021. A societal economic evaluation and return on investment (ROI) was calculated through deterministic modeling and validated using probabilistic sensitivity analysis across a range of plausible scenarios, including variations in patient throughput, training efficacy, and healthcare system parameters. RESULTS: The total societal investment in the program was €20.1 million, translating to an average cost of €1146 per participant and €1720 per Quality-Adjusted Healthcare Worker (QAHW). Deterministic modeling estimated an ROI of 478%, with program costs fully recovered in just 5.1 days. Probabilistic sensitivity analysis confirmed the robustness of these findings, with a mean ROI of 455% (95% CI 130-1029%) and a median break-even point of 5.4 days (95% CI 2.66-13.04 days). CONCLUSION: Rapid, structured ICU workforce upskilling initiatives deliver substantial economic returns and significantly expands healthcare capacity. Strategic investment in emergency workforce upskilling is economically sound and crucial for healthcare system resilience during future crises.

Topics & Concepts

WorkforceAnesthesiologyMedicineInvestment (military)Pain medicineReturn on investmentIntensive care medicineEconomicsAnesthesiaProduction (economics)MacroeconomicsEconomic growthPoliticsPolitical scienceLawSepsis Diagnosis and TreatmentDisaster Response and ManagementTrauma and Emergency Care Studies