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Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review

Jingjing Shen, Zhongming Wang

2022Frontiers in Oncology20 citationsDOIOpen Access PDF

Abstract

Most patients with advanced gastric cancer were treated with palliative therapy, which had a poor curative effect and a short survival time. In recent years, the clinical research of immune checkpoint inhibitors in advanced gastric cancer has made a breakthrough and has become an important treatment for advanced gastric cancer. The modes of immune checkpoint inhibitors in the treatment of advanced gastric cancer include single drug, combined chemotherapy, radiotherapy, and multiple immune drug combination therapy, among which combination therapy shows better clinical efficacy, and a large number of trials are currently exploring more effective combination therapy programs. In this paper, the new clinical research progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer is reviewed, with an emphasis on combination therapy.

Topics & Concepts

MedicineCancerImmune checkpointCombination therapyRadiation therapyClinical trialOncologyImmune systemChemotherapyImmunotherapyCancer therapyInternal medicineImmunologyGastric Cancer Management and OutcomesGastrointestinal Tumor Research and TreatmentCancer Immunotherapy and Biomarkers
Recent advances in the progress of immune checkpoint inhibitors in the treatment of advanced gastric cancer: A review | Litcius