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SynBiopython: an open-source software library for <i>Synthetic Biology</i>

Jing Wui Yeoh, Neil Swainston, Péter Végh, Valentin Zulkower, Pablo Carbonell, Maciej B. Holowko, Gopal Peddinti, Chueh Loo Poh

2021Synthetic Biology14 citationsDOIOpen Access PDF

Abstract

Abstract Advances in hardware automation in synthetic biology laboratories are not yet fully matched by those of their software counterparts. Such automated laboratories, now commonly called biofoundries, require software solutions that would help with many specialized tasks such as batch DNA design, sample and data tracking, and data analysis, among others. Typically, many of the challenges facing biofoundries are shared, yet there is frequent wheel-reinvention where many labs develop similar software solutions in parallel. In this article, we present the first attempt at creating a standardized, open-source Python package. A number of tools will be integrated and developed that we envisage will become the obvious starting point for software development projects within biofoundries globally. Specifically, we describe the current state of available software, present usage scenarios and case studies for common problems, and finally describe plans for future development. SynBiopython is publicly available at the following address: http://synbiopython.org.

Topics & Concepts

Python (programming language)Computer scienceSoftware engineeringSoftwareSynthetic biologyOpen sourceSoftware developmentOpen source softwareData scienceProgramming languageBioinformaticsBiologyGene Regulatory Network AnalysisMicrobial Metabolic Engineering and BioproductionGenetics, Bioinformatics, and Biomedical Research