Bile acid composition regulates the manganese transporter Slc30a10 in intestine
Tiara R. Ahmad, Sei Higuchi, Enrico Bertaggia, Allison Hung, Niroshan Shanmugarajah, Nicole C. Guilz, Jennifer R. Gamarra, Rebecca A. Haeusler
Abstract
expression in mouse ileum epithelia. These data demonstrate a previously unknown role for BAs in intestinal control of manganese homeostasis.
Topics & Concepts
ChemistryIleumBile acidTransporterBiochemistryLithocholic acidEffluxCalcitriol receptorFarnesoid X receptorReceptorNuclear receptorGeneTranscription factorDrug Transport and Resistance MechanismsTrace Elements in HealthPharmacological Effects and Toxicity Studies